ImmunoAgeing

Project publications

Meryk A, Pangrazzi L, Hagen M, Hatzmann F, Jenewein B, Jakic B, Hermann-Kleiter N, Baier G, Jylhävä J, Hurme M, Trieb K, Grubeck-Loebenstein B.
Fcμ receptor as a Costimulatory Molecule for T Cells.
Cell Rep. 2019 Mar 5;26(10):2681-2691.e5. doi: 10.1016/j.celrep.2019.02.024

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Lukas Yani S., Keller M., Melzer F.L., Weinberger B., Pangrazzi L., Sopper S., Trieb K., Lobina M., Orrù V., Fiorillo E., Cucca F.,
Grubeck-Loebenstein B.
CD8+HLADR+ regulatory T cells change with aging: They increase in number, but lose checkpoint inhibitory molecules and suppressive function.
Front. Immunol. 2018; 9:1201. doi: 10.3389/fimmu.2018.01201

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Pangrazzi L., Naismith E., Meryk A., Keller M., Jenewein B., Trieb K., Grubeck-Loebenstein B.
Increased IL-15 production and accumulation of highly differentiated CD8+ effector/memory T cells in the bone marrow of persons with Cytomegalovirus.
Front. Immunol. 2017; 8:715. doi: 10.3389/fimmu.2017.00715

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Steri M, Orrù V, Idda ML, Pitzalis M, Pala M, Zara I, Sidore C, Faà V, Floris M, Deiana M, Asunis I, Porcu E, Mulas A, Piras MG, Lobina M, Lai S, Marongiu M, Serra V, Marongiu M, Sole G, Busonero F, Maschio A, Cusano R, Cuccuru G, Deidda F, Poddie F, Farina G, Dei M, Virdis F, Olla S, Satta MA, Pani M, Delitala A, Cocco E, Frau J, Coghe G, Lorefice L, Fenu G, Ferrigno P, Ban M, Barizzone N, Leone M, Guerini FR, Piga M, Firinu D, Kockum I, Lima Bomfim I, Olsson T, Alfredsson L, Suarez A, Carreira PE, Castillo-Palma MJ, Marcus JH, Congia M, Angius A, Melis M, Gonzalez A, Alarcón Riquelme ME, da Silva BM, Marchini M, Danieli MG, Del Giacco S, Mathieu A, Pani A, Montgomery SB, Rosati G, Hillert J, Sawcer S, D'Alfonso S, Todd JA, Novembre J, Abecasis GR, Whalen MB, Marrosu MG, Meloni A, Sanna S, Gorospe M, Schlessinger D, Fiorillo E, Zoledziewska M,
Cucca F.
Overexpression of the Cytokine BAFF and Autoimmunity Risk.
N Engl J Med. 2017 Apr 27;376(17):1615-1626. doi: 10.1056/NEJMoa1610528

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